Single-cell RNA sequencing reveals Nestin+ active neural stem cells outside the central canal after spinal cord injury

Volume: 65, Issue: 2, Pages: 295 - 308
Published: May 28, 2021
Abstract
Neural stem cells (NSCs) in the spinal cord hold great potential for repair after spinal cord injury (SCI). The ependyma in the central canal (CC) region has been considered as the NSCs source in the spinal cord. However, the ependyma function as NSCs after SCI is still under debate. We used Nestin as a marker to isolate potential NSCs and their immediate progeny, and characterized the cells before and after SCI by single-cell RNA-sequencing...
Paper Details
Title
Single-cell RNA sequencing reveals Nestin+ active neural stem cells outside the central canal after spinal cord injury
Published Date
May 28, 2021
Journal
Volume
65
Issue
2
Pages
295 - 308
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