A multi-omics study links TNS3 and SEPT7 to long-term former smoking NSCLC survival

The genetic architecture of non-small cell lung cancer (NSCLC) is relevant to smoking status. However, the genetic contribution of long-term smoking cessation to the prognosis of NSCLC patients remains largely unknown. We conducted a genome-wide association study primarily on the prognosis of 1299 NSCLC patients of long-term former smokers from independent discovery ( n = 566) and validation ( n = 733) sets, and used in-silico function...