Super-enhancers: a new frontier for epigenetic modifiers in cancer chemoresistance
Abstract
Although new developments of surgery, chemotherapy, radiotherapy, and immunotherapy treatments for cancer have improved patient survival, the emergence of chemoresistance in cancer has significant impacts on treatment effects. The development of chemoresistance involves several polygenic, progressive mechanisms at the molecular and cellular levels, as well as both genetic and epigenetic heterogeneities. Chemotherapeutics induce epigenetic...
Paper Details
Title
Super-enhancers: a new frontier for epigenetic modifiers in cancer chemoresistance
Published Date
May 19, 2021
Volume
40
Issue
1
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