Dual and opposing roles of the androgen receptor in VETC-dependent and invasion-dependent metastasis of hepatocellular carcinoma

Volume: 75, Issue: 4, Pages: 900 - 911
Published: Oct 1, 2021
Abstract
Contradictory roles of the androgen receptor (AR) in hepatocellular carcinoma (HCC) metastasis have been reported. We have shown that VETC (vessels encapsulating tumor clusters) mediates invasion-independent metastasis, whereas VETC- HCCs metastasize in an invasion-dependent manner. Herein, we aimed to reveal the roles of AR in HCC metastasis.Mouse xenograft models, clinical samples, and cell models were used.AR expression was significantly...
Paper Details
Title
Dual and opposing roles of the androgen receptor in VETC-dependent and invasion-dependent metastasis of hepatocellular carcinoma
Published Date
Oct 1, 2021
Volume
75
Issue
4
Pages
900 - 911
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