TAK1 signaling is a potential therapeutic target for pathological angiogenesis
Abstract
Angiogenesis plays a critical role in both physiological responses and disease pathogenesis. Excessive angiogenesis can promote neoplastic diseases and retinopathies, while inadequate angiogenesis can lead to aberrant perfusion and impaired wound healing. Transforming growth factor β activated kinase 1 (TAK1), a member of the mitogen-activated protein kinase kinase kinase family, is a key modulator involved in a range of cellular functions...
Paper Details
Title
TAK1 signaling is a potential therapeutic target for pathological angiogenesis
Published Date
May 10, 2021
Journal
Volume
24
Issue
3
Pages
453 - 470
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Notes
History