Healthy and preeclamptic pregnancies show differences in Guanylate-Binding Protein-1 plasma levels
Abstract
The large interferon-inducible anti-angiogenic pro-inflammatory GTPase Guanylate Binding Protein-1 (GBP-1) is produced and secreted by activated endothelial cells and is highly induced by inflammatory cytokines and inhibited by angiogenic growth factors. During pregnancy a generalized mild inflammatory response is observed. During preeclampsia this generalized inflammatory response is even further activated and activation of the endothelium...
Paper Details
Title
Healthy and preeclamptic pregnancies show differences in Guanylate-Binding Protein-1 plasma levels
Published Date
Aug 1, 2021
Journal
Volume
25
Pages
18 - 24
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Notes
History