Circulating Tumor Cell Clusters Are Frequently Detected in Women with Early-Stage Breast Cancer
Abstract
The clinical relevance of circulating tumor cell clusters (CTC-clusters) in breast cancer (BC) has been mostly studied using the CellSearch®, a marker-dependent method detecting only epithelial-enriched clusters. However, due to epithelial-to-mesenchymal transition, resorting to marker-independent approaches can improve CTC-cluster detection. Blood samples collected from healthy donors and spiked-in with tumor mammospheres, or from BC patients,...
Paper Details
Title
Circulating Tumor Cell Clusters Are Frequently Detected in Women with Early-Stage Breast Cancer
Published Date
May 13, 2021
Journal
Volume
13
Issue
10
Pages
2356 - 2356
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