Heated intraperitoneal chemotherapy for colorectal cancer: game over or game on?

The abdominal cavity eventually harbours peritoneal metastatic disease in one in ten patients with colorectal cancer. This is one of the most obscure, intriguing, devastating, discouraging, and provoking manifestations of colorectal cancer1. Obscure because peritoneal metastases (PMs) are usually undetectable and almost invariably underestimated on radiological imaging. Intriguing because recent research has revealed unique properties of...