An antibody-like peptidic network for anti-angiogenesis
Abstract
Different from chemical (small molecular inhibitor) and biological (monoclonal antibody) drugs, herein, based on angiogenesis-related neuropilin-1 (NRP-1), we develop a biomimetic superstructure drug, i.e. an antibody-like peptidic network (ALPN) to achieve the high-efficient treatment of choroidal neovascularization (CNV). The ALPN in nanoparticulated formulation (ALPN-NPS) can bind NRP-1 through targeting unit and form fibrous peptidic...
Paper Details
Title
An antibody-like peptidic network for anti-angiogenesis
Published Date
Aug 1, 2021
Journal
Volume
275
Pages
120900 - 120900
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