The effect of combined sertraline and positive psychotherapy on hopelessness and suicidal ideation among patients with major depressive disorder: a randomized controlled trial

The present study was examined the effect of a combined treatment (sertraline and positive psychotherapy) compared to the pharmacotherapy (sertraline) alone on hopelessness and suicidal ideation of patients with major depressive disorder (MDD). Patients were 100 depressed outpatients treated with either combined treatment (n = 50) or pharmacotherapy alone (n = 50). Measures were taken multiple times over the course of treatment (at baseline, 2,...