Adhesion-mediated mechanosignaling forces mitohormesis

Volume: 33, Issue: 7, Pages: 1322 - 1341.e13
Published: Jul 1, 2021
Abstract
Mitochondria control eukaryotic cell fate by producing the energy needed to support life and the signals required to execute programed cell death. The biochemical milieu is known to affect mitochondrial function and contribute to the dysfunctional mitochondrial phenotypes implicated in cancer and the morbidities of aging. However, the physical characteristics of the extracellular matrix are also altered in cancerous and aging tissues. Here, we...
Paper Details
Title
Adhesion-mediated mechanosignaling forces mitohormesis
Published Date
Jul 1, 2021
Volume
33
Issue
7
Pages
1322 - 1341.e13
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