mTOR pathway and somatostatin receptors expression intratumor-heterogeneity in ileal NETs

Volume: 28, Issue: 7, Pages: 449 - 456
Published: Jul 1, 2021
Abstract
The knowledge of the molecular landscape of ileal neuroendocrine tumors (NETs) is affected by the lack of systematic studies investigating intra-tumoral heterogeneity. In this study, intra-tumoral heterogeneity was investigated in 27 primary ileal G1-NETs and their matched nodal and liver metastases in order to assess the tumor grading, the expression status of two somatostatin receptor isoforms (i.e. SSTR2A and SSTR5) and mTOR signaling...
Paper Details
Title
mTOR pathway and somatostatin receptors expression intratumor-heterogeneity in ileal NETs
Published Date
Jul 1, 2021
Volume
28
Issue
7
Pages
449 - 456
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