Cellular Senescence in Human Aldosterone-Producing Adrenocortical Cells and Related Disorders
Abstract
In situ cortisol excess was previously reported to promote cellular senescence, a cell response to stress, in cortisol-producing adenomas (CPA). The aim of this study was to explore senescence pathways in aldosterone-producing cells and related disorders, and the influence of aldosterone overproduction on in situ senescence. We analyzed 30 surgical cases of aldosterone-producing adenoma (APA), 10 idiopathic hyperaldosteronism (IHA) and 19 normal...
Paper Details
Title
Cellular Senescence in Human Aldosterone-Producing Adrenocortical Cells and Related Disorders
Published Date
May 18, 2021
Journal
Volume
9
Issue
5
Pages
567 - 567
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