Targeting Amino Acid Metabolic Vulnerabilities in Myeloid Malignancies
Abstract
Tumor cells require a higher supply of nutrients for growth and proliferation than normal cells. It is well established that metabolic reprograming in cancers for increased nutrient supply exposes a host of targetable vulnerabilities. In this article we review the documented changes in expression patterns of amino acid metabolic enzymes and transporters in myeloid malignancies and the growing list of small molecules and therapeutic strategies...
Paper Details
Title
Targeting Amino Acid Metabolic Vulnerabilities in Myeloid Malignancies
Published Date
May 20, 2021
Journal
Volume
11
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