B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors
Abstract
B lymphocyte development is dependent on the interplay between the chromatin landscape and lineage-specific transcription factors. It has been suggested that B lineage commitment is associated with major changes in the nuclear chromatin environment, proposing a critical role for lineage-specific transcription factors in the formation of the epigenetic landscape. In this report, we have used chromosome conformation capture in combination with...
Paper Details
Title
B Lymphocyte Specification Is Preceded by Extensive Epigenetic Priming in Multipotent Progenitors
Published Date
Jun 1, 2021
Journal
Volume
206
Issue
11
Pages
2700 - 2713
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