An overview of ProTide technology and its implications to drug discovery
Volume: 16, Issue: 10, Pages: 1149 - 1161
Published: May 24, 2021
Abstract
Introduction: The ProTide technology is a phosphate (or phosphonate) prodrug method devised to deliver nucleoside monophosphate (or monophosphonate) intracellularly bypassing the key challenges of antiviral and anticancer nucleoside analogs. Three new antiviral drugs, exploiting this technology, have been approved by the FDA while others are in clinical studies as anticancer agents.Areas covered: The authors describe the origin and development...
Paper Details
Title
An overview of ProTide technology and its implications to drug discovery
Published Date
May 24, 2021
Volume
16
Issue
10
Pages
1149 - 1161
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