Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education
Abstract
Beyond hemostasis, platelets actively participate in immune cell recruitment and host defense, yet their potential in the resolution of inflammatory processes remains unknown. Here, we demonstrate that platelets are recruited into the lung together with neutrophils during the onset of inflammation and alongside regulatory T (T reg) cells during the resolution phase. This partnering dichotomy is regulated by differential adhesion molecule...
Paper Details
Title
Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education
Published Date
May 20, 2021
Volume
218
Issue
7
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