Delayed brain development of Rolandic epilepsy profiled by deep learning–based neuroanatomic imaging

Although Rolandic epilepsy (RE) has been regarded as a brain developmental disorder, neuroimaging studies have not yet ascertained whether RE has brain developmental delay. This study employed deep learning–based neuroanatomic biomarker to measure the changed feature of “brain age” in RE. The study constructed a 3D-CNN brain age prediction model through 1155 cases of typically developing children’s morphometric brain MRI from open-source...