Acceleration of Trichinella spiralis worm expulsion by leukotriene B4 receptor binding inhibition
Abstract
Helminth infection typically induces a Th2 inflammatory response that is characterized by eosinophilia, high levels of IgE and mast cells. LTB4 is generated from innate immune cells, such as neutrophils, macrophages and mast cells, in response to a range of stimuli. It mainly acts on myeloid leukocytes, inducing the activation of integrins, adhesion to endothelium walls, and chemotaxis.The objective of the present study was to determine the role...
Paper Details
Title
Acceleration of Trichinella spiralis worm expulsion by leukotriene B4 receptor binding inhibition
Published Date
May 28, 2021
Journal
Volume
43
Issue
9
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