In Regard to Alcorn et al.

Published on Jun 1, 2021in International Journal of Radiation Oncology Biology Physics5.859
· DOI :10.1016/J.IJROBP.2020.12.055
Carsten Nieder30
Estimated H-index: 30
(Nordland Hospital Trust)
Source
Abstract
References7
Newest
#1Sara R. Alcorn (Johns Hopkins University)H-Index: 9
#2Jacob Fiksel (Johns Hopkins University)H-Index: 7
Last. Scott L. Zeger (Johns Hopkins University)H-Index: 104
view all 10 authors...
ABSTRACT Background To determine if a machine learning approach optimizes survival estimation for patients with symptomatic bone metastases (SBM), we developed the Bone Metastases Ensemble Trees for Survival (BMETS) to predict survival using 27 prognostic covariates. To establish relative clinical utility, we compared BMETS to two simpler Cox regression models used in this setting. Methods and Materials For 492 bone sites in 397 patients evaluated for palliative radiation therapy (RT) for SBM fr...
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#1Jon M. RichardsH-Index: 1
#2Trever BurgonH-Index: 4
Last. John W. Peabody (UCLA: University of California, Los Angeles)H-Index: 34
view all 7 authors...
PURPOSE:Addressing unwarranted clinical variation in oncology is a high priority for health systems that aspire to ensure consistent levels of high-quality and cost-effective care. Efforts to impro...
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#1Isabelle Colombet (Paris V: Paris Descartes University)H-Index: 18
#2Carole Bouleuc (Curie Institute)H-Index: 7
Last. Pascale VinantH-Index: 6
view all 8 authors...
Accessible indicators of aggressiveness of care at the end-of-life are useful to monitor implementation of early integrated palliative care practice. To determine the intensity of end-of-life care from exhaustive data combining administrative databases and hospital clinical records, to evaluate its variability across hospital facilities and associations with timely introduction of palliative care (PC). For this study designed as a decedent series nested in multicentre cohort of advanced cancer p...
6 CitationsSource
#1Vithusha Ganesh (U of T: University of Toronto)H-Index: 8
#2Stephanie Chan (U of T: University of Toronto)H-Index: 12
Last. Edward Chow (U of T: University of Toronto)H-Index: 70
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Abstract Background and purpose Single fraction radiation treatment (SFRT) is recommended for its equivalence to multiple-fraction (MF) RT in the palliation of uncomplicated bone metastases (BM). However, adoption of SFRT has been slow. Materials and methods Literature searches for studies published following 2014 were conducted using online repositories of gray literature, Ovid MEDLINE, Embase and Embase Classic, and the Cochrane Central Register of Controlled Trials databases. Results A total ...
10 CitationsSource
#1Paulien G. Westhoff (UU: Utrecht University)H-Index: 5
#2Alexander de Graeff (UU: Utrecht University)H-Index: 29
Last. Yvette M. van der Linden (LUMC: Leiden University Medical Center)H-Index: 21
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Purpose Patients with bone metastases have a widely varying survival. A reliable estimation of survival is needed for appropriate treatment strategies. Our goal was to assess the value of simple prognostic factors, namely, patient and tumor characteristics, Karnofsky performance status (KPS), and patient-reported scores of pain and quality of life, to predict survival in patients with painful bone metastases. Methods and Materials In the Dutch Bone Metastasis Study, 1157 patients were treated wi...
31 CitationsSource
#1Carsten Nieder (University of Tromsø)H-Index: 30
#2Adam PawinskiH-Index: 12
Last. Astrid Dalhaug (University of Tromsø)H-Index: 13
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Recent studies from Italy, Japan and Norway have confirmed previous reports, which found that a large variety of palliative radiotherapy regimens are used for painful bone metastases. Routine use of single fraction treatment might or might not be the preferred institutional approach. It is not entirely clear why inter-physician and inter-institution differences continue to persist despite numerous randomized trials, meta-analyses and guidelines, which recommend against more costly and inconvenie...
22 CitationsSource
#1Edward Chow (Sunnybrook Health Sciences Centre)H-Index: 70
#2Mohamed AbdolellH-Index: 28
Last. Ian F. TannockH-Index: 93
view all 7 authors...
Purpose To derive and validate a simple predictive model for survival of patients with metastatic cancer attending a palliative radiotherapy clinic. Patients and Methods We described previously a model predicting survival of patients referred for palliative radiotherapy using six prognostic factors: primary cancer site, site of metastases, Karnofsky performance score (KPS), and the fatigue, appetite, and shortness of breath subscales from the Edmonton Symptom Assessment Scale. Here we simplified...
162 CitationsSource
Cited By1
Newest
#1Sara R. Alcorn (Johns Hopkins University)H-Index: 9
#2Jacob Fiksel (Johns Hopkins University)H-Index: 7
Last. Scott L. Zeger (Johns Hopkins University)H-Index: 104
view all 10 authors...
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