Immunotherapy for the prevention of high-risk oral disorders malignant transformation: the IMPEDE trial
Abstract
Oral Potentially Malignant Disorders (OPMD) have a non-negligible malignant transformation rate of up to 8%. Loss of heterozygosity (LOH) in critical chromosomal loci has proven to be the most effective marker in defining the risk of transformation and it is found in about 28% of OPMD and may therefore identify patients carrying higher risk. To date, clinical management of OPMD is limited to surgical excision and clinical surveillance, which...
Paper Details
Title
Immunotherapy for the prevention of high-risk oral disorders malignant transformation: the IMPEDE trial
Published Date
May 17, 2021
Journal
Volume
21
Issue
1
Pages
1 - 6
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