Reconstruction of Ultra‐thin Alveolar‐capillary Basement Membrane Mimics
Abstract
Alveolar-capillary basement membrane (BM) is ultra-thin (<2 µm) extracellular matrix that maintains integral epithelial-endothelial cell layers. In vitro reconstructions of alveolar-capillary barrier supported on synthetic scaffolds closely resembling the fibrous and ultra-thin natural BM are essential in mimicking the lung pathophysiology. Although BM topology and dimensions are well known to significantly influence cellular behavior,...
Paper Details
Title
Reconstruction of Ultra‐thin Alveolar‐capillary Basement Membrane Mimics
Published Date
May 13, 2021
Journal
Volume
5
Issue
8
Pages
2000427 - 2000427
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Notes
History