ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells
Abstract
Background Oroscomucoid 3 (ORMDL3) has been linked to susceptibility of childhood asthma and respiratory viral infection. Polyinosinic-polycytidylic acid (poly I:C) is a synthetic analog of viral double-stranded RNA, a toll-like receptor 3 (TLR3) ligand and mimic of viral infection. Methods To investigate the functional role of ORMDL3 in the poly I:C-induced inflammatory response in airway epithelial cells, ORMDL3 knockdown and over-expression...
Paper Details
Title
ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells
Published Date
May 17, 2021
Journal
Volume
21
Issue
1
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