Ufmylation regulates granulosa cell apoptosis via ER stress but not oxidative stress during goat follicular atresia
Abstract
Follicular atresia is primarily caused by granulosa cell (GC) apoptosis, although the mechanisms are largely unknown. Ufmylation is a recently identified ubiquitin-like post-translational modifier that plays an important role in cell proliferation and apoptosis. The purpose of this study was to investigate the effects of Ufmylation on GC apoptosis during goat follicular atresia. Ubiquitin-fold modifier 1 (UFM1) and its target DDRGK domain...
Paper Details
Title
Ufmylation regulates granulosa cell apoptosis via ER stress but not oxidative stress during goat follicular atresia
Published Date
Jul 1, 2021
Journal
Volume
169
Pages
47 - 55
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