Recovery of roseoflavin from a recombinant Streptomyces davaonensis strain by using biphasic aqueous systems

BACKGROUND Roseoflavin (RoS) is a naturally occurring red color riboflavin analog compound, produced mainly by Streptomyces davaonensis , with a rising profile owing to its antibacterial potential. However, there is a lack of strategies for its downstream processing and the existing ones are limited to chromatographic techniques involving harmful reagents. The use of aqueous two‐phase systems (ATPS), a liquid–liquid extraction method, is...