Differences in the eyelid and buccal microbiome of glaucoma patients receiving long-term administration of prostaglandin analog drops

To investigate the differences in the eyelid and buccal microbiomes between patients receiving long-term prostaglandin analogs for open-angle glaucoma (PG-OAG) and naive-OAG patients by using metagenomics. Eyelid and buccal samples were collected from 30 PG-OAG and 32 naive-OAG patients. The taxonomic composition of the microbiome was obtained via 16S rRNA gene sequencing, operational taxonomic unit analysis, and diversity analysis. Differential...