Reply to: “The importance of evaluating coronary sinus blood flow during the coronary sinus reducer treatment”

Several mechanisms could potentially explain the poor response to coronary sinus Reducer (CSR) therapy: inappropriate patient selection, cardiac venous system heterogeneity, coronary sinus size, incomplete device endothelization, coronary artery disease phenotype, and progression, and limited myocardial ischemia at baseline [ [1] Baldetti L. Colombo A. Banai S. et al. Coronary sinus reducer non-responders: insights and perspectives....