LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
Abstract
null While the initial pathology of Parkinson’s disease and other α-synucleinopathies is often confined to circumscribed brain regions, it can spread and progressively affect adjacent and distant brain locales. This process may be controlled by cellular receptors of α-synuclein fibrils, one of which was proposed to be the LAG3 immune checkpoint molecule. Here, we analyzed the expression pattern of LAG3 in human and mouse brains. Using a variety...
Paper Details
Title
LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies
Published Date
Apr 26, 2021
Journal
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