Discovering the Mutational Profile of Early Colorectal Lesions: A Translational Impact

Volume: 13, Issue: 9, Pages: 2081 - 2081
Published: Apr 25, 2021
Abstract
Colorectal cancer (CRC) develops through a multi-step process characterized by the acquisition of multiple somatic mutations in oncogenes and tumor-suppressor genes, epigenetic alterations and genomic instability. These events lead to the progression from precancerous lesions to advanced carcinomas. This process requires several years in a sporadic setting, while occurring at an early age and or faster in patients affected by hereditary...
Paper Details
Title
Discovering the Mutational Profile of Early Colorectal Lesions: A Translational Impact
Published Date
Apr 25, 2021
Journal
Volume
13
Issue
9
Pages
2081 - 2081
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