Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract
Abstract
Transforming growth factor β (TGFβ) signaling plays critical roles in reproductive development and function. TGFβ ligands signal through the TGFβ receptor type 2 (TGFBR2)/TGFBR1 complex. As TGFBR2 and TGFBR1 form a signaling complex upon ligand stimulation, they are expected to be equally important for propagating TGFβ signaling that elicits cellular responses. However, several genetic studies challenge this concept and indicate that disruption...
Paper Details
Title
Functional similarity between TGF-beta type 2 and type 1 receptors in the female reproductive tract
Published Date
Apr 29, 2021
Journal
Volume
11
Issue
1
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