Eco-friendly micellar HPTLC technique for the simultaneous analysis of co-formulated antibiotic cefoperazone and sulbactam in pure form and vial pharmaceutical formulation

A rapid, sensitive, and eco-friendly micellar high-performance thin-layer chromatography (HPTLC) technique for the simultaneous analysis of cefoperazone and sulbactam in pure and vial pharmaceutical formulation was developed. Merck aluminum HPTLC plates covered with silica gel 60 F254 were used as the stationary phase; acetone‒ethanol‒ethyl acetate‒2% sodium dodecyl sulfate‒glacial acetic acid (3:2:4:1:0.5, V/V) were used as the mobile phase....