Human convalescent plasma protects K18-hACE2 mice against severe respiratory disease
Abstract
SARS-CoV-2 is the causative agent of COVID-19 and human infections have resulted in a global health emergency. Small animal models that reproduce key elements of SARS-CoV-2 human infections are needed to rigorously screen candidate drugs to mitigate severe disease and prevent the spread of SARS-CoV-2. We and others have reported that transgenic mice expressing the human angiotensin-converting enzyme 2 (hACE2) viral receptor under the control of...
Paper Details
Title
Human convalescent plasma protects K18-hACE2 mice against severe respiratory disease
Published Date
May 27, 2021
Journal
Volume
102
Issue
5
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