Multigene Panels Enjoy a Broad Psychological Acceptance by Patients

Dr. Idos says that one concern raised by critics of multigene panels is the high VUS rate and the potential for distress and uncertainty among these variant carriers. “However, our study showed that the psychologic response of VUS carriers matched the response of the patients testing negative.” With the increased use of germline multigene panel testing for assessing inherited cancer risk, little is known about the acceptance of these tests—or...