Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models
Abstract
Tumor-associated macrophages (TAMs) are critical components of the tumor microenvironment (TME) in prostate cancer. Commonly used orthotopic models do not accurately reflect the complete TME of a human patient or the natural initiation and progression of a tumor. Therefore, genetically engineered mouse models are essential for studying the TME as well as advancing TAM-targeted therapies. Two common transgenic (TG) models of prostate cancer are...
Paper Details
Title
Characterization of tumor‐associated macrophages in prostate cancer transgenic mouse models
Published Date
May 5, 2021
Journal
Volume
81
Issue
10
Pages
629 - 647
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