Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease

Volume: 12, Issue: 2, Pages: 665 - 687
Published: Jan 1, 2021
Abstract
Background and AimsThe pathophysiology of the inflammatory bowel disease collagenous colitis (CC) is poorly described. Our aim was to use RNA sequencing of mucosal samples from patients with active CC, CC in remission, refractory CC, ulcerative colitis (UC), and control subjects to gain insight into CC pathophysiology, identify genetic signatures linked to CC, and uncover potentially druggable disease pathways.MethodsWe performed whole...
Paper Details
Title
Transcriptomic Profiling of Collagenous Colitis Identifies Hallmarks of Nondestructive Inflammatory Bowel Disease
Published Date
Jan 1, 2021
Volume
12
Issue
2
Pages
665 - 687
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