Distinct Repopulation Activity in Hu-Mice Between CB- and LPB- CD34＋ Cells by Enrichment of Transcription Factors
Abstract
Human CD34＋ hematopoietic stem cells can reconstitute the human hematopoietic system when transplanted into immunocompromised mice after irradiation. Human leukapheresis peripheral blood (LPB)- and cord blood (CB)-derived CD34＋ cells have a similar capacity to reconstitute myeloid lineage cells in a humanized mice (hu-mice) model. However, potent stem cells, such as CB-CD34＋ cells, efficiently reconstitute the lymphoid system in vivo compared to...
Paper Details
Title
Distinct Repopulation Activity in Hu-Mice Between CB- and LPB- CD34＋ Cells by Enrichment of Transcription Factors
Published Date
Apr 30, 2021
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