Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death
Abstract
Heart failure is an inexorably progressive disease with a high mortality, for which heart transplantation (HTx) remains the gold standard treatment. Currently, donor hearts are primarily derived from patients following brain stem death (BSD). BSD causes activation of the sympathetic nervous system, increases endothelin levels, and triggers significant inflammation that together with potential myocardial injury associated with the transplant...
Paper Details
Title
Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death
Published Date
Jul 1, 2021
Journal
Volume
169
Pages
105631 - 105631
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Notes
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