Endocarditis prophylaxis in adult congenital heart disease

The risk for infective endocarditis (IE) is increased in adults with congenital heart disease compared to the general population. Therefore, prophylactic measures are of utmost importance. Antibiotic prophylaxis (AP) for IE has been in use for more than six decades. However, a paradigm shift regarding the recommendations for AP occurred in the last two decades mainly due to the missing evidence for the effectiveness of AP as well as due to...