Insulin secretion is a strong predictor for need of insulin therapy in patients with new‐onset diabetes and HbA1c of more than 10%: A post hoc analysis of the EDICT study

Aim To identify predictors of response to glucose‐lowering therapy in patients with new‐onset diabetes and very high HbA1c (>10%). Methods The study included EDICT participants with an initial HbA1c of more than 10% (N = 104). All subjects received a 75‐g oral glucose tolerance test (OGTT) before initiation of therapy, and then were randomized to receive: (a) initial triple therapy with metformin, pioglitazone and exenatide versus (b)...