A novel therapeutic modality using CRISPR-engineered dendritic cells to treat allergies
Abstract
Despite the important roles of dendritic cells (DCs) in airway allergies, current therapeutic strategies such as drugs, allergen immunotherapy and biologics haven't been targeted at them. In this study, we established a promising DC-based therapeutic approach for the alleviation of allergic rhinitis (AR)-associated allergic reactions, using clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-mediated targeted gene disruption....
Paper Details
Title
A novel therapeutic modality using CRISPR-engineered dendritic cells to treat allergies
Published Date
Jun 1, 2021
Journal
Volume
273
Pages
120798 - 120798
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