Understanding the effect of mechanical forces on ovarian cancer progression

Objective Mechanical forces including tension, compression, and shear stress are increasingly implicated in tumor progression and metastasis. Understanding the mechanisms behind epithelial ovarian cancer (EOC) progression and metastasis is critical, and this study aimed to elucidate the effect of oscillatory and constant tension on EOC. Methods SKOV-3 and OVCAR-8 EOC cell lines were placed under oscillatory tension for 3 days and compared to...