Age-associated proinflammatory elastic fiber remodeling in large arteries
Abstract
Elastic fibers are the main components of the extracellular matrix of the large arterial wall. Elastic fiber remodeling is an intricate process of synthesis and degradation of the core elastin protein and microfibrils accompanied by the assembly and disassembly of accessory proteins. Age-related morphological, structural, and functional proinflammatory remodeling within the elastic fiber has a profound effect upon the integrity, elasticity,...
Paper Details
Title
Age-associated proinflammatory elastic fiber remodeling in large arteries
Published Date
Jun 1, 2021
Volume
196
Pages
111490 - 111490
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