Diagnosis of Autoimmune Pancreatitis: A Protocol for Clinical Practice

Published on Jun 30, 2021
· DOI :10.1002/9781119570097.CH45
Nicolò de Pretis8
Estimated H-index: 8
Antonio Amodio13
Estimated H-index: 13
Luca Frulloni11
Estimated H-index: 11
#1Kazuichi Okazaki (Kansai Medical University)H-Index: 85
#2Kazushige Uchida (Kansai Medical University)H-Index: 30
: IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder recognized as a novel clinical entity with either synchronous or metachronous multi-organ involvement. Patients with IgG4-RD show diffuse or focal organ enlargement and mass-forming or nodular/thickened lesions with abundant infiltration of IgG4-positive plasmacytes and fibrosis, and such patients respond well to steroid treatment. It should be differentiated from mimics by a combination of serum IgG4 level, imaging features, and h...
10 CitationsSource
#1Nicolò de Pretis (University of Verona)H-Index: 8
#2Giulia De MarchiH-Index: 6
Last. Luca FrulloniH-Index: 58
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Purpose of review Clinical management of autoimmune pancreatitis changed over the last years. The lack of high-quality studies, probably due to the relative rarity of the disease, has not fully clarified many diagnostic and therapeutic aspects. Aim of this review is to overview the literature from a clinical point of view, focusing on diagnostic and therapeutic approach to this complicated disease. Recent findings They have been focused mainly on the risk of misdiagnosing a cancer. Many signific...
1 CitationsSource
#2Björn Lindkvist (University of Gothenburg)H-Index: 51
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BackgroundContrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) and quantitative-elastography endoscopic ultrasound (QE-EUS) are considered useful tools for the evaluation of solid pancreatic ...
36 CitationsSource
#1Kazuichi Okazaki (Kansai Medical University)H-Index: 85
#2Suresh T. Chari (Mayo Clinic)H-Index: 103
Last. Tooru Shimosegawa (Tohoku University)H-Index: 95
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Abstract Background and aims The International Consensus Diagnostic Criteria (ICDC) for AIP has proposed two distinctive type of AIP, type 1 and type 2, and enabled us first to differentiate two types of AIP each other. By initial steroid treatment for induction of remission, remission can be successfully induced in almost all subjects with type 1 and type 2 AIP. As relapse rate in type 1 AIP is significantly higher than in type 2 AIP, there has been ongoing debate on how to treat effectively re...
71 CitationsSource
#1Milena Ilic (University of Kragujevac)H-Index: 13
#2Irena Ilic (University of Kragujevac)H-Index: 9
Cancer of the pancreas remains one of the deadliest cancer types. Based on the GLOBOCAN 2012 estimates, pancreatic cancer causes more than 331000 deaths per year, ranking as the seventh leading cause of cancer death in both sexes together. Globally, about 338000 people had pancreatic cancer in 2012, making it the 11th most common cancer. The highest incidence and mortality rates of pancreatic cancer are found in developed countries. Trends for pancreatic cancer incidence and mortality varied con...
438 CitationsSource
#1Atsushi Kanno (Tohoku University)H-Index: 18
#1Atsushi Kanno (Tohoku University)H-Index: 39
Last. Tooru Shimosegawa (Tohoku University)H-Index: 95
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Background and Aims Histopathologic examination is critical for diagnosing autoimmune pancreatitis (AIP). However, specimens obtained using EUS-guided FNA (EUS-FNA) are not recommended for histopathologic diagnosis because of inadequate sample size volume. We evaluated EUS-FNA efficacy for AIP diagnosis using a 22G needle. Methods Seventy-eight patients exhibiting the imaging characteristics indicative of AIP in the pancreatic parenchyma and pancreatic duct underwent EUS-FNA with a 22G needle at...
57 CitationsSource
#1Giulia De Marchi (University of Verona)H-Index: 6
#2Salvatore Paiella (University of Verona)H-Index: 23
Last. Luca Frulloni (University of Verona)H-Index: 58
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4 CitationsSource
#1Phil A. Hart (Mayo Clinic)H-Index: 29
#2Michael J. Levy (Mayo Clinic)H-Index: 107
Last. Suresh T. Chari (Mayo Clinic)H-Index: 103
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Objective Idiopathic duct-centric chronic pancreatitis (IDCP), also known as type 2 autoimmune pancreatitis (AIP), is an uncommon subtype of AIP. International Consensus Diagnostic Criteria for IDCP propose that the diagnosis requires pancreatic histology and/or concurrent IBD. We examined our experience with IDCP (type 2 AIP) to assess the appropriateness of these criteria, and identify unique characteristics in patients presenting with acute pancreatitis. Design We reviewed the Mayo Clinic AIP...
34 CitationsSource
#1Francesco VitaliH-Index: 2
#2Torsten HansenH-Index: 27
Last. Luca FrulloniH-Index: 58
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ObjectivesA diagnosis of benign lesions (BLs) is reported in 5% to 21% of pancreatoduodenectomies performed for neoplasms; no data for body-tail resections are available. The aims were to investigate the frequency and characterize the BLs mimicking cancer in the head and the body-tail of the pancrea
12 CitationsSource
#1Tsukasa Ikeura (Kansai Medical University)H-Index: 19
#2Riccardo Manfredi (University of Verona)H-Index: 24
Last. Luca Frulloni (University of Verona)H-Index: 58
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Background: International consensus diagnostic criteria (ICDC) have been proposed to classify autoimmune pancreatitis (AIP) in type 1, type 2, or not otherwise specified. Objective: Aim was to apply the ICDC to an Italian series of patients to evaluate the incidence and clinical profiles among different subtypes of AIP. Methods: we re-evaluated and classified 92 patients diagnosed by Verona criteria, according to the ICDC. Results: Out of 92 patients, 59 (64%) were diagnosed as type 1, 17 (18%) ...
27 CitationsSource
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