Controversies on the possible role of immune checkpoint inhibitors in pediatric cancers: balancing irAEs and efficacy
Abstract
Pediatric cancers are not the equivalent of adult cancers occurring at a younger age and the prospect of immunotherapy in children has not been received with the same enthusiasm as in the adult setting. Although most pediatric malignancies are considered immunologically cold, we are learning more about PD-L1 expression, tumor mutational burden, and microsatellite instability in several pediatric cancers. The side effects of immunotherapy are an...
Paper Details
Title
Controversies on the possible role of immune checkpoint inhibitors in pediatric cancers: balancing irAEs and efficacy
Published Date
Apr 20, 2021
Journal
Volume
107
Issue
4
Pages
276 - 281
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