Phase‐ and state‐dependent modulation of breathing pattern by preBötzinger complex somatostatin expressing neurons
Abstract
As neuronal subtypes are increasingly categorized, delineating their functional role is paramount. The preBötzinger complex (preBötC) subpopulation expressing the neuropeptide somatostatin (SST) is classified as mostly excitatory, inspiratory-modulated and not rhythmogenic. We further characterized their phenotypic identity: 87% were glutamatergic and the balance were glycinergic and/or GABAergic. We then used optogenetics to investigate their...
Paper Details
Title
Phase‐ and state‐dependent modulation of breathing pattern by preBötzinger complex somatostatin expressing neurons
Published Date
Nov 15, 2021
Journal
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