Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics

Volume: 12
Published: Apr 12, 2021
Abstract
Prostate cancer (PRAD) is a major cause of cancer-related deaths. Current monotherapies show limited efficacy due to often rapidly emerging resistance. Combination therapies could provide an alternative solution to address this problem with enhanced therapeutic effect, reduced cytotoxicity, and delayed the appearance of drug resistance. However, it is prohibitively cost and labor-intensive for the experimental approaches to pick out synergistic...
Paper Details
Title
Prediction of Synergistic Drug Combinations for Prostate Cancer by Transcriptomic and Network Characteristics
Published Date
Apr 12, 2021
Volume
12
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