Fabrication of Rapidly Separable Microneedles for Transdermal Delivery of Metformin on Diabetic Rats
Volume: 110, Issue: 8, Pages: 3004 - 3010
Published: Aug 1, 2021
Abstract
In this work, the rapidly separable microneedles (MNs) consisted of needle-tips and supporting bases have been fabricated by a step-by-step coating method. Poly (vinyl alcohol) (PVA) have been used to prepare the needle-tips of MNs in which they are capped on the solvable supporting bases consisted of sodium bicarbonate, poly (vinyl pyrolidone) (PVP), and tartaric acid (TA) (NaHCO3/PVP/TA). After insertion into the skin, the needle-tips can be...
Paper Details
Title
Fabrication of Rapidly Separable Microneedles for Transdermal Delivery of Metformin on Diabetic Rats
Published Date
Aug 1, 2021
Volume
110
Issue
8
Pages
3004 - 3010
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