Ferroptosis, radiotherapy, and combination therapeutic strategies
Abstract
Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently been revealed to play an important role in radiotherapy-induced cell death and tumor suppression, and to mediate the synergy between radiotherapy and immunotherapy. In this review, we summarize known as well as putative mechanisms underlying the crosstalk between...
Paper Details
Title
Ferroptosis, radiotherapy, and combination therapeutic strategies
Published Date
Apr 23, 2021
Journal
Volume
12
Issue
11
Pages
836 - 857
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Notes
History