Defects in early secretory pathway transport machinery components and neurodevelopmental disorders
Abstract
The early secretory pathway, provisionally comprising of vesicular traffic between the endoplasmic reticulum (ER) and the Golgi apparatus, occurs constitutively in mammalian cells. Critical for a constant supply of secretory and plasma membrane (PM) materials, the pathway is presumably essential for general cellular function and survival. Neurons exhibit a high intensity in membrane dynamics and protein/lipid trafficking, with differential and...
Paper Details
Title
Defects in early secretory pathway transport machinery components and neurodevelopmental disorders
Published Date
Mar 30, 2021
Journal
Volume
32
Issue
8
Pages
851 - 869
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