Improvements in stem cell to beta-cell differentiation for the treatment of diabetes

Since the generation of human embryonic and induced pluripotent stem cells, regenerative cell-based approaches for the treatment of diabetes have gained popularity. One strategy is to generate an unlimited source of insulin-producing pancreatic β-cells from human pluripotent stem cells. As such, major effort continues to be placed in creating efficient differentiation protocols that generate functional β-like cells from human pluripotent stem...